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Aurantio-obtusin
CAS No. : 67979-25-3
Biological Activity：Aurantio-obtusin is an anthraquinone isolated from Semen Cassiae, with anti-Inflammatory, anti-oxidative, anti-coagulating and anti-hypertension activities[2][3]. Aurantio-obtusin relaxes systemic arteries through endothelial PI3K/AKT/eNOS-dependent signaling pathway in rats, thus acts as a new potential vasodilator[2]. Aurantio-obtusin inhibits allergic responses in IgE-mediated mast cells and anaphylactic models and is potential for treatment for allergy-related diseases[3].
Research Area：Inflammation/Immunology|Cardiovascular Disease
Targets：Akt|PI3K
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Related Small Molecules:Akt/NF-κB/JNK-IN-1;Umbralisib hydrochloride;Topoisomerase I/II inhibitor 3;Cyclovirobuxine D;Rigosertib sodium;Tenalisib R Enantiomer;AKTide-2T;PI3kδ inhibitor 1;Sennidin A;PI3K/VEGFR2-IN-1;MS98;PP2A Cancerous-IN-1;1,3-Dicaffeoylquinic acid;PI3Kδ-IN-1;PI-103-d8;PI3Kα-IN-8;Artemisiane E;PI-103 Hydrochloride;IC-87114;PI3K/mTOR Inhibitor-6;Artemisinin-d3;PI3K-IN-10;SF2523;AS1949490;PI3K-IN-29;TD52 dihydrochloride;PI3K/mTOR Inhibitor-1;LM22B-10;PI3K-IN-26
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