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Almonertinib
CAS No. : 1899921-05-1
Biological Activity：Almonertinib (HS-10296) is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 (IC50: 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib is used for the research of the non-small cell lung cancer[2].
Research Area：Cancer
Targets：EGFR
Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;FDA-Approved Drug Library; Anti-Cancer Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Differentiation Inducing Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Hepatitis C Virus Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Targeted Diversity Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;FDA-Approved Anticancer Drug Library;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:NSC81111;pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;BMS-690514;Osimertinib-13C,d3;EGFR-IN-5;FGFR2-IN-3;Genistein;Epertinib hydrochloride;UNC-CA359;Osimertinib mesylate;AV-412 free base;Nelipepimut-S;Falnidamol;HER2-IN-6;PROTAC EGFR degrader 7;CHMFL-EGFR-202;Avitinib;Naquotinib;Lavendustin A;EAI001;EGFR/HER2/CDK9-IN-2;Cyasterone;DP-C-4;Allitinib
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