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A-582941 dihydrochloride
CAS No. : 848591-90-2
Biological Activity：A-582941 dihydrochloride is a potent, selective and brain-penetrant partial agonist of α7 nAChR, with Kis of 10.8 and 16.7 nM in rat brain membranes and human frontal cortex, respectively. A-582941 dihydrochloride also binds to human 5-HT3 receptor with a Ki of 150 nM. A-582941 has the potential for cognitive deficits associated with various neurodegenerative and psychiatric disorders research[2].
Research Area：Neurological Disease
Targets：nAChR|5-HT Receptor
Related Small Molecules:F 13714;Mosapride-d5;Spinosad;Nuciferine;Pyrantel;Renzapride;LY 344864 racemate;Harmine hydrochloride;Valerenic acid;Arotinolol;Melitracen-d6 hydrochloride;WAY-100635;Nelotanserin;Flupentixol-d4 dihydrochloride;Cariprazine-d6 hydrochloride;Tetrahydro-β-carboline;NS 9283;CP-809101;Myosmine-d4
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