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Aβ1–42 aggregation inhibitor 1
CAS No. : 2439107-75-0
Biological Activity：Aβ1-42 aggregation inhibitor 1 inhibits AChE (acetylcholinesterase) and BuChE (butyrylcholinesterase) with the IC50 value of 2.64 μM and 1.29 μM, respectively. Aβ1-42 aggregation inhibitor 1 inhibits self-mediated Aβ1-42 aggregation by 51.29% at a concentration of 25 μM. Aβ1-42 aggregation inhibitor 1 has the potential for the research of anti-Alzheimer’s disease.
Research Area：Neurological Disease
Targets：Amyloid-β|Cholinesterase (ChE)
Related Small Molecules:β-Amyloid (13-27);Saikosaponin C;β-Amyloid (1-42), (rat/mouse) (TFA);Piperilate;β-Amyloid (12-28) (TFA);BuChE-IN-5;Ginsenoside Rg1;MDR-1339;AChE/BChE-IN-10;Timosaponin AIII;Trimyristin;AChE-IN-10;Isoimperatorin;Pseudocoptisine chloride;Itopride-d6 hydrochloride;β-Amyloid (11-22);Sinapine thiocyanate;sEH/AChE-IN-1;AChE-IN-11;20(S)-Ginsenoside Rg3;β-Amyloid (31-35);Heliosupine;(-)-Cyclopenin;Aβ-IN-1;Leptomerine
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