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3,6-DMAD dihydrochloride
CAS No. : 2226511-77-7
Biological Activity：3,6-DMAD dihydrochloride, an acridine derivative, is a potent IRE1α-XBP1s pathway inhibitor. 3,6-DMAD dihydrochloride promotes IL-6 secretion via the IRE1α-XBP1s pathway. 3,6-DMAD dihydrochloride inhibits IRE1α oligomerization and endoribonuclease (RNase) activity. 3,6-DMAD dihydrochloride can be used for research of cancer[2].
Research Area：Cancer
Targets：IRE1
Related Small Molecules:MKC8866;IXA4;4μ8C;GSK2850163 hydrochloride;B I09;IRE1α kinase-IN-3;IXA6;GSK2850163 (S enantiomer);IRE1α kinase-IN-5;KIRA6;MKC3946;Kira8;PAIR2;IRE1α kinase-IN-2;Toyocamycin;IRE1α kinase-IN-4;KIRA-7;KIRA9;STF-083010;IRE1α kinase-IN-1;MKC9989
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