For research use only. We do not sell to patients.
1,11b-Dihydro-11b-hydroxymedicarpin
CAS No. : 210537-04-5
Biological Activity：1,11b-Dihydro-11b-hydroxymedicarpin (11b-Hydroxy-11b,1-dihydromedicarpin) is a pterocarpan from Ononis viscosa subsp. breviflora is a Medicarpin derivative. Medicarpin, a natural pterocarpan, heals cortical bone defect by activation of Notch and Wnt canonical signaling pathways[2]. Medicarpin prevents arthritis in post-menopausal conditions by arresting the expansion of TH17 cells and pro-inflammatory cytokines. Medicarpin down-regulates pro-inflammatory cytokines like TNF-α, IL-6 and IL-17A, while up-regulates anti-inflammatory cytokine IL-10 in arthritis (CIA) model of mice[3].
Research Area：Inflammation/Immunology
Targets：Interleukin Related
Related Small Molecules:AX-024;Ginsenoside F3;Perakizumab;PNRI-299;CTX-471;Ac-YVAD-CHO;Deucravacitinib;Mulberroside A;NFAT Transcription Factor Regulator-1;IL-17A antagonist 1;Kansuinine B;Ginsenoside Rc;5(S)15(S)-DiHETE;IL-17A inhibitor 2;Anti-Mouse IL-1b Antibody;Raleukin;Ossirene;VGX-1027;RCGD423;Clazakizumab;Reslizumab;Gamma-glutamylcysteine TFA;Tyrphostin A1;Interleukin (IL)-6 Receptor;Satralizumab;Sirukumab;Siltuximab
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
