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Zoniporide hydrochloride hydrate

CAS No. : 863406-85-3

Biological Activity：Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 (IC₅₀=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC₅₀=59 nM)^[2].

Research Area：Cardiovascular Disease

Targets：Na+/H+ Exchanger (NHE)

Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Anti-Cardiovascular Disease Compound Library;Human Metabolite Library;Coagulation and Anti-coagulation Compound Library;

Related Small Molecules:Cariporide;FR183998 free base;Tenapanor;BI-9627;Eniporide hydrochloride;Rimeporide hydrochloride;Monensin sodium salt;NHE3-IN-1;EIPA hydrochloride;NHE3-IN-2

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