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Zaprinast
CAS No. : 37762-06-4
Biological Activity：Zaprinast (M&B 22948) is an inhibitor of cGMP-selective Phosphodiesterases(PDEs). Zaprinast is a G protein-coupled receptor (GPR) 35 agonist which activates rat GPR35 strongly and activates human GPR35 moderately[2]. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects[3].
Research Area：Neurological Disease|Cardiovascular Disease|Endocrinology
Targets：Phosphodiesterase (PDE)|GPR35
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