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Vamotinib
CAS No. : 1416241-23-0
Biological Activity:Vamotinib (PF-114) is a potent, selective and orally active tyrosine kinase inhibitor. Vamotinib inhibits the autophosphorylation of BCR/ABL and BCR/ABL-T315I. Vamotinib induces apoptosis. Vamotinib shows anti-proliferative and anti-tumor activity. Vamotinib has the potential for the research of resistant philadelphia chromosome-positive (Ph+) leukemia.
Research Area:Cancer
Targets:Bcr-Abl
Related Small Molecules:AT9283;Bafetinib;Pivanex;SNIPER(ABL)-039;Flumatinib mesylate;IHMT-TRK-284;SNIPER(ABL)-049;Olverembatinib;GNF-2;CT-721;SNIPER(ABL)-015;GNF-5;BCR-ABL-IN-4;SNIPER(ABL)-033;CHMFL-ABL-039;BCR-ABL-IN-6;c-ABL-IN-2;SNIPER(ABL)-058;ON 146040;HG-7-85-01;CHMFL-ABL/KIT-155;Radotinib-d6;BCR-ABL-IN-1;SIAIS178
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