For research use only. We do not sell to patients.
Vactosertib Hydrochloride
CAS No. : 1352610-25-3
Biological Activity：Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect[2].
Research Area：Cancer
Targets：TGF-β Receptor
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;TGF-beta/Smad Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Reprogramming Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Rare Diseases Drug Library;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Osteogenesis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:ML347;LDN193189 (GMP);TGFβRI-IN-4;ALK5-IN-6;TGFβ-IN-1;p-nitro-Pifithrin-α;Chromenone 1;OD36;ALK5-IN-32;SB-505124 hydrochloride;K02288;ALK5-IN-28;LY-364947;LY3200882;Itacnosertib;J-1063;Maohuoside A;ALK5-IN-27;Galunisertib;ALK2-IN-4 succinate;SB-431542 (GMP);A 83-01;A 77-01;MU1700;Dorsomorphin;ALK5-IN-34;SM 16;SB 525334
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
