Toceranib

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Toceranib

CAS No. : 356068-94-5

Biological Activity:Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors[2].

Research Area:Cancer

Targets:VEGFR|c-Kit|PDGFR

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;

Related Small Molecules:(Z)-FeCP-oxindole;VEGFR-2-IN-24;BMS-690514;PROTAC VEGFR-2 degrader-2;Henatinib;PI3K/VEGFR2-IN-1;c-Kit-IN-5-1;Flumatinib mesylate;IHMT-TRK-284;PDGFRα/FLT3-ITD-IN-2;PP58;Hydroxytanshinone IIA;Chiauranib;Foretinib;ZM323881 hydrochloride;Zeteletinib;Pexidartinib;PTC299;ENMD-2076 Tartrate;Aflibercept;SU5408;MAZ51;R1530

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