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SSR180711 hydrochloride
CAS No. : 446031-79-4
Biological Activity：SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. SSR180711 hydrochloride can act on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). SSR180711 hydrochloride increases glutamatergic neurotransmission, ACh release and long-term potentiation (LTP) in the hippocampus.
Research Area：Neurological Disease
Targets：nAChR
Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;Anti-Alzheimer’s Disease Compound Library;
Related Small Molecules:Spinosad;Pyrantel;NS 9283;Myosmine-d4;Benzethonium chloride;Dihydro-β-erythroidine;A-867744;Catestatin;Asoxime dichloride;α7 nAchR-JAK2-STAT3 agonist 1;AR-R17779 hydrochloride;Mecamylamine hydrochloride;Tropisetron;Zolunicant;S16961;NS3861;(±)-Anatoxin A fumarate;Oxantel;PHA-543613 dihydrochloride;(S)-Dinotefuran;Nelonicline citrate;Coclaurine;Cytisinicline;NS 1738;Asoxime-d4 dichloride;(R)-(+)-Anatabine;nAChR modulator-1;BNC210
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