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SMCypI C31

CAS No. : 2649904-85-6

Biological Activity：SMCypI C31 is a non-peptidic cyclophilin inhibitor with potent peptidyl-prolyl cis/trans isomerases (PPIase) inhibitory activity (IC₅₀ of 0.1 µM). SMCypI C31 shows pangenotype anti-HCV activity with EC₅₀s ranging from 1.20 to 7.76 μM for genotype 1a, 1b, 2a, 3a, and 5a HCV subgenomic replicons (HCV-SGRs) and chimeric genotype 2a/4a HCV-SGRs. SMCypI C31 disrupts the cyclophilin A-NS5A interaction^[2].

Research Area：Infection

Targets：HCV

Related Small Molecules:HCV-IN-30;HCV-IN-38;Sennidin A;HCV-IN-31;Radalbuvir;Grazoprevir potassium salt;FGI-106 tetrahydrochloride;BMS-986144;Oenothein B;Triton X-45(n=4);Mecarbinate;Artemisinin-d3;TTP-8307;HCV-IN-34;Miravirsen;Ciluprevir;MK-0608;Setrobuvir;Astodrimer;Elbasvir

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