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Sirt1/2-IN-1
CAS No. : 2402779-21-7
Biological Activity：Sirt1/2-IN-1 (Compound 7) is a SIRT1 and SIRT2 inhibitor with IC50 values of 1.81, 2.10 and 20.5 µg/mL against SIRT1, SIRT2 and SIRT3, respectively. Sirt1/2-IN-1 displays activity in hyperacetylation of α-tubulin protein with an IC50 of 32.05 µg/mL. Sirt1/2-IN-1 shows prominent anticancer activity.
Research Area：Cancer
Targets：Microtubule/Tubulin|Sirtuin
Related Small Molecules:PROTAC Sirt2 Degrader-1;SIRT1/2/3-IN-1;Tirbanibulin dihydrochloride;Tilavonemab;Cambinol;JGB1741;Tau tracer 1;Dolastatin 10;Nicotinamide-d4;Ceratamine A;Batabulin sodium;OXi8007;Antitumor agent-68;Sirtuin modulator 3;Dictyostatin;Tubulin inhibitor 6;Oryzalin;Resveratrol;Tubulin inhibitor 25;Fmoc-MMAE;Taltobulin;SRT 1720 Hydrochloride;Tubulin inhibitor 16;Epothilone B;TN-16;Maytansinol
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