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SCH442416
CAS No. : 316173-57-6
Biological Activity：SCH442416 is a potent, selective and brain-penetrant antagonist of adenosine A2A receptor (A2AR), with Kis of 0.048 and 0.5 nM for human and rat A2AR respectively. SCH442416 displays more than 23000-fold selectivity over A1R, A2BR, and A3R (Ki=1111, 10000, and 10000 nM, respectively). SCH442416 can be used for imaging of adenosine A2A receptors in rat and primate brain[2].
Research Area：Neurological Disease
Targets：Adenosine Receptor
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Related Small Molecules:MRS 1523;APNEA;MIPS521;Derenofylline;FSCPX;Theobromine-d3;Inosine-13C;Norisoboldine;N-0861 racemate;Xanthine amine congener dihydrochloride;LUF6096;A1/A3 AR antagonist 1;ATL-801;Istradefylline;Doxofylline-d6;A1AR antagonist 3;MRS1186;A2A/A3 AR antagonist-1;A2AAR/HDAC-IN-2;MRS-1191;MRS5698;GP531;Imaradenant;PSB-0788
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