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SAG hydrochloride
CAS No. : 2095432-58-7
Biological Activity：SAG hydrochloride is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG hydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo[2][3].
Research Area：Cancer
Targets：Smo
Related Screening Libraries:Bioactive Compound Library Plus;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library; Anti-Aging Compound Library;Reprogramming Compound Library;Anti-Pancreatic Cancer Compound Library;
Related Small Molecules:Saikosaponin B1;MRT-10;LEQ506;RL-0070933;20(S)-Hydroxycholesterol;Sonidegib;PF-5274857 hydrochloride;MRT-83 hydrochloride;TPB15;CUR61414;SANT-1;SAG-d3;SMANT hydrochloride;BMS-833923;SMO-IN-2;SMO-IN-1;IHR-1;Purmorphamine (GMP);IHR-Cy3;MRT-14;MK-4101;DY131
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