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Sacubitril
CAS No. : 149709-62-6
Biological Activity：Sacubitril (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19[2][3].
Research Area：Infection|Cardiovascular Disease
Targets：Neprilysin
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Drug Repurposing Compound Library;Anti-Cardiovascular Disease Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Targeted Diversity Library;Rare Diseases Drug Library;EMA-Approved Drug Library;
Related Small Molecules:TD-0212;Thiorphan;Phosphoramidon Disodium;Sacubitril-13C4 hemicalcium salt;Sacubitrilat;SCH 42495 racemate;NEP-IN-2;Thiorphan-d5;Racecadotril-d5;SCH-42354;Racecadotril;Sacubitril hemicalcium salt;NEP-In-1;Candoxatril;Sampatrilat;SQ28603;Opiorphin
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