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RWJ 50271

CAS No. : 162112-37-0

Biological Activity：RWJ 50271 is an selective and orally active inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC₅₀ of 5.0 μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated cell adhesion.

Research Area：Inflammation/Immunology

Targets：Integrin

Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Targeted Diversity Library;Protein-protein Interaction Inhibitor Library;

Related Small Molecules:GRGDSPK;Integrin Binding Peptide;Cyclo(Arg-Gly-Asp-D-Phe-Cys);Zaurategrast ethyl ester sulfate;HSDVHK-NH2;Lifitegrast sodium;TC-I 15;α2β1 Integrin Ligand Peptide;Integrin modulator 1;Veltuzumab;GRGDSP TFA;Cyclo(-RGDfK) TFA;Zalunfiban;K34c;THI0019;RGD;Arg-Gly-Asp-Ser (TFA);BIRT 377;αvβ1 integrin-IN-1;RGD-4C;LXW7;Fradafiban;Firategrast;EILEVPST;Valategrast hydrochloride

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