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Ruboxistaurin hydrochloride
CAS No. : 169939-93-9
Biological Activity：Ruboxistaurin (LY333531) hydrochloride is an orally active, selective PKC beta inhibitor (Ki=2 nM). Ruboxistaurin hydrochloride exhibits ATP dependent competitive inhibition of PKC beta I with an IC50 of 4.7 nM. Ruboxistaurin hydrochloride inhibits PKC beta II with an IC50 of 5.9 nM[2].
Research Area：Metabolic Disease
Targets：PKC
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Epigenetics Compound Library;Kinase Inhibitor Library;TGF-beta/Smad Compound Library;FDA-Approved Drug Library;Drug Repurposing Compound Library;Reprogramming Compound Library;Anti-diabetic Compound Library;Macrocyclic Compound Library;Oxygen Sensing Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Neurodegenerative Disease-related Compound Library;EMA-Approved Drug Library;Cancer Stem Cells Compound Library;Coagulation and Anti-coagulation Compound Library;
Related Small Molecules:[Ala107]MBP(104-118) TFA;BJE6-106;Myelin Basic Protein;Staurosporine;PKC-iota inhibitor 1;Hypericin;Malantide;PKCiota-IN-2 formic;PF-4950834;C8 Dihydroceramide;SC-9;DL-erythro-Dihydrosphingosine;Safingol;ZIP;Psychosine-d5;TPPB;Enzastaurin;Protein Kinase C (19-31);Protein kinase inhibitor H-7 dihydrochloride;Teleocidin A1;Ro 31-8220;[Ser25] Protein Kinase C (19-31);CGP60474
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