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RepSox
CAS No. : 446859-33-2
Biological Activity：RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC50 value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes[2].
Research Area：Metabolic Disease
Targets：TGF-β Receptor
Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;TGF-beta/Smad Compound Library;Reprogramming Compound Library;Anti-diabetic Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Anti-Colorectal Cancer Compound Library ;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Osteogenesis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:ML347;LDN193189 (GMP);TGFβRI-IN-4;ALK5-IN-6;TGFβ-IN-1;p-nitro-Pifithrin-α;Chromenone 1;OD36;ALK5-IN-32;SB-505124 hydrochloride;K02288;ALK5-IN-28;LY-364947;LY3200882;Itacnosertib;J-1063;Maohuoside A;ALK5-IN-27;Galunisertib;ALK2-IN-4 succinate;SB-431542 (GMP);A 83-01;A 77-01;MU1700;Dorsomorphin;ALK5-IN-34;SM 16;SB 525334
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