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Remdesivir-d4
Biological Activity：Remdesivir-d4 is deuterium labeled Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[2].
Research Area：Infection
Targets：DNA/RNA Synthesis|SARS-CoV
Related Small Molecules:Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;P1788;SARS-CoV-2-IN-33;Thymidine-13C5,15N;NSC 617145;GRL-0496;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;6-Thio-2′-Deoxyguanosine;Antitumor agent-74;Grazoprevir potassium salt;Risdiplam;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;TH287 hydrochloride
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Structurally and synthetically diverse biologically active compounds；
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