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R112
CAS No. : 575474-82-7
Biological Activity：R112 is a fast and reversible inhibitor of spleen tyrosine kinase (Syk) kinase. R112 inhibits Syk kinase activity with an IC50 value of 226 nM and a Ki value of 96 nM. R112 inhibits IgE-FcεRI signaling pathway. R112 can be used for the research of allergic rhinitis.
Research Area：Inflammation/Immunology
Targets：Syk
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;
Related Small Molecules:Lanraplenib monosuccinate;OXSI-2;SYK/JAK-IN-1;PRT062607 Hydrochloride;MNS;TAK-659 hydrochloride;Syk Inhibitor II dihydrochloride dihydrate;Fostamatinib-d9;R406 free base;Fostamatinib Disodium;GSK2646264;Cevidoplenib;TAS05567;Midostaurin-d5;BAY 61-3606 dihydrochloride;Syk Kinase Peptide Substrate;Entospletinib;Gusacitinib;SRX3207;Cerdulatinib;Syk-IN-3;GSK143 dihydrochloride
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