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QH536
CAS No. : 2754254-07-2
Biological Activity:QH536 (Compound 29) is a potent HMGCR degrader with an EC50 of 0.22 μM. QH536 has no side-effect of inducing cholesterol accumulation in cells. QH536 shows anti-inflammatory and can be used for cardiovascular disease and nonalcoholic steatohepatitis research.
Research Area:Metabolic Disease|Inflammation/Immunology|Cardiovascular Disease
Targets:HMG-CoA Reductase (HMGCR)
Related Small Molecules:β-Amyrin acetate;SR12813;Cerivastatin;Meglutol;Hesperetin 7-O-glucoside;Monacolin J;β-Amyrin palmitate;HMG499;Clinofibrate;Mevastatin;S-2E
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