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PROTAC Bcl2 degrader-1
CAS No. : 2378801-85-3
Biological Activity：PROTAC Bcl2 degrader-1 (Compound C5) is a PROTAC based on Cereblon ligand, which potently and selectively induces the degradation of Bcl-2 (IC50, 4.94 μM; DC50, 3.0 μM) and Mcl-1 (IC50, 11.81 μM) by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1/Bcl-2 dual inhibitor Nap-1.
Research Area：Cancer
Targets：Bcl-2 Family|PROTACs
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;BI-3812;PROTAC VEGFR-2 degrader-2;Pyridoclax;dTAGV-1-NEG;CCT367766 formic;PUMA BH3 TFA;Dehydrocorydaline;HDAC6 degrader-1;PROTAC Axl Degrader 2;PhosTAC7;MS98;JPS014;PROTAC PARP1 degrader;MD-224;FKBP12 PROTAC dTAG-7;Bufarenogin;Murizatoclax;SJ10542;MS8815;RIP2 Kinase Inhibitor 4;PROTAC EGFR degrader 7;Obatoclax;SJ995973;CYD-2-11;CC-885-CH2-PEG1-NH-CH3;dFKBP-1;MI-389;BSJ-4-116
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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