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Ponesimod

CAS No. : 854107-55-4

Biological Activity：Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P₁, with an IC₅₀ of 6 nM in a radioligand binding assay. Ponesimod activates S1P₁-mediated signal transduction with high potency (EC₅₀=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation^[2][3].

Research Area：Inflammation/Immunology

Targets：LPL Receptor

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;FDA-Approved Drug Library;Drug Repurposing Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Targeted Diversity Library;Rare Diseases Drug Library;EMA-Approved Drug Library;

Related Small Molecules:GSK2018682;Ozanimod hydrochloride;BMS-986020 sodium;S1p receptor agonist 2;ONO-9780307;Siponimod hemifumarate;S1P2 antagonist 1;S1P1 agonist III;Ceralifimod;Ki16425;H2L 5765834;S1PR1 agonist 2;RP101442;S1PR1 agonist 1;CS-2100;ASP1126;1-Oleoyl lysophosphatidic acid;Ex26;RP-001 hydrochloride;VPC 23019;CYM-5541;LPA1 receptor antagonist 1;Autotaxin-IN-6;Zectivimod;CYM5442 hydrochloride;PF-543 Citrate;LPA2 antagonist 1;LPA2 antagonist 2

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