Pimethixene

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Pimethixene

CAS No. : 314-03-4

Biological Activity:Pimethixene is antihistamine and antiserotonergic compound, acts as an antimigraine agent.
Pimethixene is a highly potent antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors, with pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively.

Research Area:Neurological Disease|Endocrinology

Targets:5-HT Receptor|Histamine Receptor

Related Small Molecules:F 13714;Mosapride-d5;Nuciferine;Tripelennamine;Renzapride;Brompheniramine-d6 maleate;LY 344864 racemate;Samelisant;Harmine hydrochloride;Chlorphenoxamine;Valerenic acid;H3 receptor-MO-1;Diphenhydramine;Arotinolol;ABT-239;Melitracen-d6 hydrochloride;WAY-100635;Nelotanserin;Flupentixol-d4 dihydrochloride;Cariprazine-d6 hydrochloride

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