PDZ1i

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PDZ1i

CAS No. : 2083618-79-3

Biological Activity:PDZ1i is a potent, BBB-penetrated and specific MDA-9/Syntenin inhibitor. PDZ1i inhibits crucial GBM (glioblastoma multiforme) signaling involving FAK and EGFRvIII. PDZ1i reduces MMP secretion. PDZ1i can improve survival of brain tumor-bearing mice and reduce tumor invasion.

Research Area:Cancer

Targets:EGFR|FAK|MMP

Related Small Molecules:NSC81111;pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;BMS-690514;WAY-170523;CTTHWGFTLC, CYCLIC;Osimertinib-13C,d3;Harringtonolide;Edaravone;EGFR-IN-5;FAK-IN-8;FGFR2-IN-3;D-Isofloridoside;Genistein;Epertinib hydrochloride;UNC-CA359;BI-4464;Chondroitin sulfate;Osimertinib mesylate;AV-412 free base;Nelipepimut-S;Ginsenoside F4;Falnidamol;HER2-IN-6;PROTAC EGFR degrader 7;CHMFL-EGFR-202;ND-336

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