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Paxilline
CAS No. : 57186-25-1
Biological Activity：Paxilline is an indole alkaloid mycotoxin from Penicillium paxilli, acts as a potent BK channels inhibitor by an almost exclusively closed-channel block mechanism. Paxilline also inhibits the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) with IC50s between 5 μM and 50 μM for differing isoforms. Paxilline possesses significant anticonvulsant activity[2][3].
Research Area：Neurological Disease
Targets：Calcium Channel|Potassium Channel
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