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Panaxadiol
CAS No. : 19666-76-3
Biological Activity：Panaxadiol (20(R)-Panaxadiol) is an orally active HIF-1α/STAT3 inhibitor. Panaxadiol can suppress HIF-1α and STAT3 then lead to downregulation of programmed cell death-ligand 1 (PD-L1) expression. Panaxadiol shows anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities[2].
Research Area：Cancer
Targets：STAT|PD-1/PD-L1|HIF/HIF Prolyl-Hydroxylase
Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library Plus;Bioactive Compound Library Plus;Epigenetics Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Metabolism/Protease Compound Library;Stem Cell Signaling Compound Library;Natural Product Library;Anti-Cancer Compound Library;Small Molecule Immuno-Oncology Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Lipid Compound Library;Oxygen Sensing Compound Library;Medicine Food Homology Compound Library;Terpenoids Library;Orally Active Compound Library;Glutamine Metabolism Compound Library;Traditional Chinese Medicine Active Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Cancer Natural Product Library;Protein-protein Interaction Inhibitor Library;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Cirsilineol;TC-S 7009;Ochromycinone;C188-9;STAT3-IN-10;PD-1/PD-L1-IN-15;Glucosamine-13C hydrochloride;C188;HIF1-IN-3;Niclosamide monohydrate;PD-1/PD-L1-IN 5 TFA;Prolyl Hydroxylase inhibitor 1;STAT3-IN-1;STAT3 degrader-1;Glucosamine-13C6,15N hydrochloride;HIF-PHD-IN-1;PD-1/PD-L1-IN-25;PM-81I;Morusin;Nifuroxazide-13C6;AS1810722;AKBA;LW6;α7 nAchR-JAK2-STAT3 agonist 1;PD-1/PD-L1-IN-18;HP590;Eupalinolide K
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