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OBI-3424
CAS No. : 2097713-68-1
Biological Activity:OBI-3424 (TH-3424) is a prodrug that is selectively converted by AKR1C3 (aldo-keto reductase 1C3) to a potent DNA-alkylating agent. OBI-3424 can be used for hepatocellular carcinoma, castrate-resistant prostate cancer, and acute lymphoblastic leukemia (ALL) research.
Research Area:Cancer
Targets:DNA Alkylator/Crosslinker
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Targeted Diversity Library;Anti-Liver Cancer Compound Library ;Anti-Prostate Cancer Compound Library;
Related Small Molecules:Anticancer agent 11;Tesirine;DC10SMe;Duocarmycin TM;Prednimustine;Sibiromycin;Lurbinectedin;Phenylacetic acid mustard;PR-104A;Duocarmycin SA;Duocarmycin DM free base;Imifoplatin;NCI172112;Satraplatin;Trioxsalen;Duocarmycin MA;Miriplatin (hydrate)
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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