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NS1643
CAS No. : 448895-37-2
Biological Activity:NS1643 is a partial agonist of human ether-a-go-go-related gene (hERG) K(+) channels with an EC50 of 10.5 μM. NS1643 has distinct effects on erg2 (Kv11.2) currents by reducing channel inactivation especially at high concentrations. NS1643 increases the repolarization reserve and exhibits an interesting new antiarrhythmic approach[2].
Research Area:Others
Targets:Autophagy|Potassium Channel
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Autophagy Compound Library;Covalent Screening Library;Neuroprotective Compound Library;Potassium Channel Compound Library;
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