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Nrf2/HO-1 activator 2

Biological Activity：Nrf2/HO-1 activator 2 (compound 13m), difluoro-substituted derivative, is a potent Nrf2/HO-1 activator. Nrf2/HO-1 activator 2 has neuroprotective and antioxidant effects through the Nrf2/HO-1 pathway mediated by phosphorylation of ERK1/2, JNK, or Akt in PC12 cells. Nrf2/HO-1 activator 2 can be used in the research of Parkinson’s disease (PD).

Research Area：Neurological Disease

Targets：Akt|Keap1-Nrf2|Reactive Oxygen Species|JNK|ERK

Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Akt/NF-κB/JNK-IN-1;Chitoheptaose heptahydrochloride;JNK3 inhibitor-2;N-Acetyl-D-cysteine;Topoisomerase I/II inhibitor 3;CYPMPO;Mangiferin;Antioxidant agent-5;Cyclovirobuxine D;Curcumin;ROS-ERS inducer 1;AKTide-2T;Glucosamine-13C hydrochloride;L-Ascorbic acid sodium salt;D-Isofloridoside;Sennidin A;L-Carnitine-d3 hydrochloride;Antroquinonol;Licochalcone D;MS98;Euparin;PP2A Cancerous-IN-1;RH-EDA;1,3-Dicaffeoylquinic acid;Corynoxeine;Antitumor agent-68;Echinocystic acid;Glucosamine-13C6,15N hydrochloride

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