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Naphthofluorescein
CAS No. : 61419-02-1
Biological Activity：Naphthofluorescein inhibits the interaction between HIF-1 and Mint3.
Naphthofluorescein suppresses Mint3-dependent HIF-1 activity and glycolysis in cancer cells and macrophages without cytotoxicity in vitro and adverse effect in vivo. Naphthofluorescein is also a fluorescent pH-sensitive probe that can be used for functional Cerenkov imaging[2].
Research Area：Cancer
Targets：HIF/HIF Prolyl-Hydroxylase
Related Small Molecules:TC-S 7009;Glucosamine-13C hydrochloride;HIF1-IN-3;Prolyl Hydroxylase inhibitor 1;Glucosamine-13C6,15N hydrochloride;HIF-PHD-IN-1;AKBA;LW6;HIF-2α-IN-5;HIF-1/2α-IN-2;GEM-5;HIF-1/2α-IN-1;Roxadustat;Daprodustat;Acetylarenobufagin;Zifcasiran;Acriflavine hydrochloride;BAY 87-2243;PHD-1-IN-1;PT-2385;ZINC13466751;(Rac)-Dencichine;Enarodustat;HIF-2α-IN-6;ENMD-1198
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