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MK-2894

CAS No. : 1006036-87-8

Biological Activity：MK-2894 is a potent, selective, orally active and high affinity (K_i=0.56 nM) full antagonist against E prostanoid receptor 4 (EP4 receptor) (IC₅₀=2.5 nM). MK-2894 possesses potent anti-inflammatory activity in animal models of pain/inflammation and can be used for the research of arthritis^[2].

Research Area：Inflammation/Immunology|Endocrinology

Targets：Prostaglandin Receptor

Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Endocrinology Compound Library;Angiogenesis-Related Compound Library;Targeted Diversity Library;

Related Small Molecules:Omidenepag isopropyl;DG-041;8-Isoprostaglandin E2;BAY-6672;trans-Isoferulic acid;GSK-269984A;KMN-80;SC 51089;p-Hydroxycinnamic acid;Pexopiprant;Dinoprost;Sulprostone;Prostaglandin E2;CAY10471 Racemate;Fevipiprant;TG6-10-1;Cicaprost;ER-819762;MRE-269-d6;ONO-8130;KAG-308;KF 13218;Prostaglandin E2-d4

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