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Mirodenafil dihydrochloride
CAS No. : 862189-96-6
Biological Activity：Mirodenafil (SK3530) dihydrochloride is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor. Mirodenafil dihydrochloride is a glucocorticoid receptor (GR) modulator Mirodenafil dihydrochloride activates the Wnt/β-catenin signaling pathway by downregulating Dkk1 expression. Mirodenafil dihydrochloride can be used for the research of erectile dysfunction (ED), Alzheimer’s disease (AD) and systemic sclerosis (SSc)[2][3].
Research Area：Endocrinology|Inflammation/Immunology|Neurological Disease
Targets：Phosphodiesterase (PDE)|Wnt|Glucocorticoid Receptor|β-catenin|Apoptosis
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;FDA-Approved Drug Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Reprogramming Compound Library;Endocrinology Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Neuroprotective Compound Library;Anti-Breast Cancer Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Anti-Colorectal Cancer Compound Library ;Antidepressant Compound Library;Human Metabolite Library;Nuclear Receptor Compound Library;Osteogenesis Compound Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Senazodan hydrochloride;(E/Z)-HA155;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;ATX inhibitor 22;Carbazeran citrate;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Bay 60-7550;BC11-38
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