Minocycline

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Minocycline

CAS No. : 10118-90-8

Biological Activity:Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect[2][3][4][5][6][7].

Research Area:Cancer|Infection|Metabolic Disease|Inflammation/Immunology|Neurological Disease|Cardiovascular Disease

Targets:Calcium Channel|Potassium Channel|HIF/HIF Prolyl-Hydroxylase|Bacterial|Antibiotic|MDM-2/p53|Apoptosis

Related Small Molecules:Physalin A;Bomedemstat ditosylate;Sandramycin;LLO (91-99);Gepotidacin;Enpp/Carbonic anhydrase-IN-1;GK563;Benidipine hydrochloride;Calpeptin;Oritavancin;Lobetyolin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;CaV1.3 antagonist-1;14-Deoxyandrographolide;BJE6-106

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