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MEK/PI3K-IN-2
CAS No. : 2281803-33-4
Biological Activity：MEK/PI3K-IN-2 (compound 6s) is a potent MEK/PI3K inhibitor, with IC50 values of 352 nM (MEK1), 107 nM (PI3Kα), and 137 nM (PI3Kδ), respectively. MEK/PI3K-IN-2 suppresses pAKT and pERK1/2 levels. MEK/PI3K-IN-2 shows anti-proliferative activity against tumor cell lines.
Research Area：Cancer
Targets：MEK|PERK|PI3K
Related Small Molecules:Avutometinib;Umbralisib hydrochloride;Topoisomerase I/II inhibitor 3;Rigosertib sodium;Tenalisib R Enantiomer;PI3kδ inhibitor 1;Cobimetinib racemate;PI3K/VEGFR2-IN-1;1,3-Dicaffeoylquinic acid;PI3Kδ-IN-1;PI-103-d8;EBI-1051;PI3Kα-IN-8;PI-103 Hydrochloride;IC-87114;CHMFL-EGFR-202;PI3K/mTOR Inhibitor-6;PI3K-IN-10;SF2523;PI3K-IN-29;PI3K/mTOR Inhibitor-1;PI3K-IN-26;GSK-F1;Serabelisib;Amdizalisib;BI-847325;AMG PERK 44
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