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LY-411575
CAS No. : 209984-57-6
Biological Activity：LY-411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), and also inhibits Notch S3 cleavage with IC50 of 0.39 nM.
Research Area：Neurological Disease
Targets：Notch|γ-secretase|Apoptosis
Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Neuronal Signaling Compound Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Neurodegenerative Disease-related Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Cancer Stem Cells Compound Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;γ-Secretase modulator 4;GK563;Calpeptin;Lobetyolin;ELN318463;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D
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