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LDN-212854

CAS No. : 1432597-26-6

Biological Activity：LDN-212854 is a bone morphogenetic protein (BMP) inhibitor that potently inhibits ALK2 (IC_{50_{: 1.3 nM). LDN-212854 also inhibits ALK1 (IC₅₀: 2.40 nM). LDN-212854 can be used in the research of fibrodysplasia ossificans progressive and cancers, such as hepatocellular carcinoma (HCC)^[2].}}

Research Area：Cancer

Targets：TGF-β Receptor

Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;TGF-beta/Smad Compound Library;Anti-Cancer Compound Library;Reprogramming Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Osteogenesis Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:ML347;LDN193189 (GMP);TGFβRI-IN-4;ALK5-IN-6;TGFβ-IN-1;p-nitro-Pifithrin-α;Chromenone 1;OD36;ALK5-IN-32;SB-505124 hydrochloride;K02288;ALK5-IN-28;LY-364947;LY3200882;Itacnosertib;J-1063;Maohuoside A;ALK5-IN-27;Galunisertib;ALK2-IN-4 succinate;SB-431542 (GMP);A 83-01;A 77-01;MU1700;Dorsomorphin;ALK5-IN-34;SM 16;SB 525334

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