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JR-AB2-011
CAS No. : 2411853-34-2
Biological Activity：JR-AB2-011 is a selective mTORC2 inhibitor with an IC50 value of 0.36 μM. JR-AB2-011 inhibits mTORC2 activity by blocking Rictor-mTOR association (Ki: 0.19 μM). JR-AB2-011 has anti-glioblastoma multiforme (GBM) properties.
Research Area：Cancer
Targets：mTOR
Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Glucose Metabolism Compound Library;Targeted Diversity Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Cyclovirobuxine D;WYE-354;L-Leucine-1-13C,15N;PI-103-d8;Palomid 529;PI-103 Hydrochloride;RMC-5552;OXA-01;L-Leucine-15N;PI3K/mTOR Inhibitor-6;PI3K/mTOR Inhibitor-1;HDACs/mTOR Inhibitor 1;Chromeceptin;hSMG-1 inhibitor 11e;PI3Kα/mTOR-IN-1;RapaLink-1;Torin 1;Dihydromyricetin;PI3K/mTOR Inhibitor-4;L-Leucine-13C6,15N;PI3K/mTOR Inhibitor-7;VS-5584;Dihydroevocarpine;Torin 2;Polyphyllin I;MHY1485
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