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IOX1
CAS No. : 5852-78-8
Biological Activity：IOX1, 5-Carboxy-8-hydroxyquinoline, is a potent broad‐spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 μM, 2.3 μM, 1.8 μM, 0.1 μM and 1.4 μM, respectively[2]. IOX1 also inhibits ALKBH5[3].
Research Area：Cancer
Targets：Histone Demethylase
Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Histone Modification Research Compound Library; Anti-Cancer Compound Library;Chemical Probe Library;Anti-Cancer Metabolism Compound Library;Transcription Factor-Targeted Library;
Related Small Molecules:Bomedemstat ditosylate;LSD1/ER-IN-1;PBIT;JQKD82;KDOAM-25 citrate;GSK-J1 lithium salt;S2116;LSD1-IN-16;TAK-418;NCGC00247743;DS17701585;KDM2B-IN-3;S2101;LSD1/2-IN-3;KDM5-IN-1;GSK467;S2157;PFI-90;FY-56;Eicosapentaenoic Acid;LSD1-IN-20;KDM5A-IN-1;Bizine;Procaine-d4 hydrochloride
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