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Hydrochlorothiazide
CAS No. : 58-93-5
Biological Activity：Hydrochlorothiazide (HCTZ), an orally active diuretic drug of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[2][3].
Research Area：Metabolic Disease|Cardiovascular Disease|Cancer
Targets：Potassium Channel|TGF-beta/Smad
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;Bioactive Compound Library Plus;Peptidomimetic Library;
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