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HIV-1 inhibitor-30

CAS No. : 2132412-77-0

Biological Activity：HIV-1 inhibitor-30 (compound 10i) is a potent HIV-1 inhibitor with an EC₅₀ value of 40 nM and an IC₅₀ value of 80 nM for HIV-1 RT DNA polymerase. HIV-1 inhibitor-30 has highly antiretroviral activity against seven non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistant HIV-1 strains (RT-K103N; RT-Y181C; RT-K103N,Y181C; RT-L100I,K103N; RT-Y188L; RT-K103N,G190A; RT-K103N,V108I) with IC₅₀s of 0.04~1.42 μM. HIV-1 inhibitor-30 can be used for researching AIDS.

Research Area：Infection|Inflammation/Immunology

Targets：HIV

Related Small Molecules:HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;FC131;Peritassine A;Flavopiridol;TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA;Apelin-36(rat, mouse);Ulonivirine;Islatravir;HIV-1 inhibitor-19

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