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HE 3286
CAS No. : 1001100-69-1
Biological Activity:HE 3286 is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. HE 3286 is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. HE 3286 freely penetrates the blood brain barrier in mice. HE 3286 can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis[2][3].
Research Area:Metabolic Disease|Inflammation/Immunology|Neurological Disease
Targets:NF-κB
Related Small Molecules:Akt/NF-κB/JNK-IN-1;Icariside F2;IKKγ NBD Inhibitory Peptide TFA;Mangiferin;Antioxidant agent-5;ALPK1-IN-1;Regaloside A;IMD-ferulic;SN52;5-Aminosalicylic Acid-D3 hydrochloride;Ginsenoside Rg1;Echinulin;Licochalcone D;QNZ;BIZ 114;NF-κΒ activator 1;Berbamine;NF-κΒ activator 2;20(S)-Ginsenoside Rg3;Ginsenoside Rd;Morusin;(R)-(-)-Ibuprofen;Ro 106-9920;Armepavine;Laquinimod;S-Allylmercaptocysteine
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