For research use only. We do not sell to patients.
HDAC/Top-IN-1
CAS No. : 2411379-14-9
Biological Activity：HDAC/Top-IN-1 is an orally active and pan HDAC/Top dual inhibitor with IC50s of 0.036 μM, 0.14 μM, 0.059 μM, 0.089 μM and 9.8 μM for HDAC1, HDAC2, HDAC3, HDAC6 and HDAC8. HDAC/Top-IN-1 efficiently induces apoptosis with S cell-cycle arrest in HEL cells. HDAC/Top-IN-1 has exhibits excellent in vivo antitumor efficacy.
Research Area：Cancer
Targets：Topoisomerase|HDAC
Related Small Molecules:Gepotidacin;Topoisomerase I/II inhibitor 3;(R)-Camptothecin-d5;Pivanex;Crotonoside;MPT0B390;Topoisomerase II inhibitor 8;FLT3-IN-13;RSC133;TP3011;HDAC1/6-IN-1;HDAC/HSP90-IN-4;JPS014;TAS-103 dihydrochloride;HDAC-IN-4;Rebeccamycin;HDAC-IN-27;1-Alaninechlamydocin;SKLB-23bb;Tacedinaline;AZD5099;TP0480066;Topoisomerase I inhibitor 4;Camptothecin;Corydamine
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
