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GSK5182
CAS No. : 877387-37-6
Biological Activity：GSK5182 is a highly selective and orally active inverse agonist of estrogen-related receptor γ (ERRγ) with an IC50 of 79 nM. GSK5182 does not interact with other nuclear receptors, including ERRα or ERα. GSK5182 also induces reactive oxyen species (ROS) generation in hepatocellular carcinoma (HCC)[2][3].
Research Area：Cancer|Cardiovascular Disease
Targets：Reactive Oxygen Species|Estrogen Receptor/ERR
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