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GBR 12935
CAS No. : 76778-22-8
Biological Activity：GBR 12935 is a potent, and selective dopamine reuptake inhibitor, with the binding constant (Kd) of 1.08 nM in COS-7 cells. GBR 12935 stimulates the locomotion activity in different mice strains but fails to induce stereotypy. Thus, GBR 12935 also prevents the d-Fenfluramine-induced head-twitch response in mice[2][3][4].
Research Area：Neurological Disease
Targets：Dopamine Transporter
Related Small Molecules:Diclofensine;13-Hydroxyisobakuchiol;Fipexide;Vanoxerine;SPD-473 citrate;Diclofensine-d3 hydrochloride;Pseudoisocyanine iodide;Bisacodyl;AHN 1-055 hydrochloride;BMS-466442;Tesofensine;Dasotraline hydrochloride;DOV-216,303 Free Base;J-147;Centanafadine-d7 hydrochloride;Centanafadine hydrochloride
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