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Fipronil-13C6
Biological Activity：Fipronil-13C6 is the 13C-labeled Fipronil. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.
Research Area：Inflammation/Immunology
Targets：GABA Receptor|Cytochrome P450
Related Small Molecules:SKF89976A hydrochloride;SR9186;AMG-208;mGAT-IN-1;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Hypericin;Alpidem;FG8119;Valerenic acid;Galeterone;Ranitidine;Picrotoxinin;Bergapten;Ginsenoside Rd;Miltirone;Etifoxine-13C,d3;Adipiplon;AS1810722;Gabazine;Isoglycycoumarin;Broflanilide;Fluxametamide;Polygalaxanthone III
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