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Fatostatin hydrobromide
CAS No. : 298197-04-3
Biological Activity：Fatostatin hydrobromide (125B11 hydrobromide), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin hydrobromide binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin hydrobromide decreases the transcription of lipogenic genes in cells. Fatostatin hydrobromide possesses antitumor properties, and lowers hyperglycemia in ob/ob mice[2].
Research Area：Cancer
Targets：Fatty Acid Synthase (FASN)
Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Lipid Metabolism Compound Library ;
Related Small Molecules:UCM05;Pedunculoside;Lycorine;Orlistat;HS80;Cerulenin;Praeruptorin B;Albaspidin AP;FT113;Pseudoprotodioscin;TVB-3664;Leelamine-d4 hydrochloride;Leelamine hydrochloride;FASN-IN-4;BI 99179;Anti-Mouse Fas Ligand Antibody;FASN-IN-1;Dihydrocurcumin;Agrimol B;PF429242 dihydrochloride;FGH10019;FASN-IN-3;trans-C75;GSK2194069;Betulin;trans-Chalcone;TVB-3166
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