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ELA-32(human) TFA
Biological Activity：ELA-32(human) TFA is a potent, high affinity apelin receptor agonist (IC50=0.27 nM; Kd=0.51 nM). ELA-32(human) TFA exhibits no binding GPR15 and GPR25. ELA-32(human) TFA activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32(human) TFA also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. ELA-32(human) TFA stimulates angiogenesis in HUVEC cells.
Targets：Apelin Receptor (APJ)
Related Small Molecules:ML221;Apelin-13 TFA;ML233;[Pyr1]-Apelin-13;APJ receptor agonist 5;APJ receptor agonist 1;ELA-11(human) TFA;NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal);AM-8123;Elabela(19-32) TFA;MM 07;APJ receptor agonist 4;Azelaprag;ELA-21 (human);APJ receptor agonist 6;MM 54;CMF019;NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal);Apelin agonist 1;APJ receptor agonist 3
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